Laviana

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Analytical Chemistry Service

-CGMP Release (COA)
-HPLC, GC Method Development and Validation
-Forced Degradation Studies
-Reference Standard Qualification
-CMC Preparation and Review

Discovery chemistry services

-Hit-to-lead and lead optimization
-Optimizing selectivity, binding, or inhibition activity to improve potency and selectivity
-Enhancing ADMET and pharmacokinetic properties
-Conducting SAR analyses
-Novelty assessment
-Backup molecules and fast-follow candidates

Custom synthesis

- Research and development of chemical processes suitable for the synthesis of preclinical and phase I/II study materials from the original medicinal chemistry route
- Process improvement of existing chemical process
- Validation of process technical package provided by customers
-Production of non-GMP material and advanced intermediates up to hundreds of kilograms

Process R & D and Production

- Medicinal chemistry scaffold and building blocks
- Scale-up of selected compounds for further evaluation
- Reference compound, assay standard, and metabolite
- Key and advanced intermediates
- Synthetic pathway design, evaluation and route scouting
We had delivered with greater than 90% success rate either from known synthetic route or an improved chemical process

Laviana provides integrated chemistry outsourcing service to pharmaceutical and biopharmaceutical companies worldwide. We provided services to pharmaceutical and biopharmaceutical companies in the

Informex USA 2014, Jan. 22^th to 24^th, 2014, Miami, booth number: 714

CPhI worldwide 2013, Oct. 22th to 24th, 2013, Frankfurt, booth number: Hall 4.2 42G31-09

CPhI China 2013￡?June 25th to 27th, 2013, Shanghai, booth number: W2C02

CPhI Japan 2013￡?April 24th to 26th, 2013, Tokyo, booth number: C24

From June 13, 2012 to June 14, 2012" European Fine Chemicals Exhibition" in Barcelona, Spain

From March 25, 2012 to March 29, 2012 "ACS" of California, San Diego

From March 21, 2012 to March 23, 2012" world pharmaceutical raw materials ( Japan ) Exhibition" in Japan, Tokyo, booth No.: A27

From February 15, 2012 to February 17, 2012," the United States of America Fine Chemical Industry Exhibition" the United States, New Orleans, booth No.: 1807