Green chemistry is no longer an unfamiliar concept. Various green technologies are revolutionizing the industrial scale-up of new drug production, transforming the efficiency and processes involved in drug development.

A new drug molecule typically undergoes a multi-step journey from the initial substrate to the final product.

While the yield of each individual step may not significantly impact small-scale synthesis, it becomes a critical factor when transitioning to large-scale production. The introduction of enzymes in the early stages of a project to enhance yields offers numerous advantages and can wield a significant influence on later-stage project development. Many drug molecules are chiral, and enzyme catalysis holds a distinct advantage over chemical methods in the synthesis of chiral molecules.

Enzyme-catalyzed reactions exhibit high specificity and selectivity, especially in the catalysis of chiral molecules. These reactions often occur in conditions with a substantial aqueous phase and minimal organic solvent usage, maintaining relatively low temperatures, thus ensuring mild reaction conditions. As catalysts, enzymes require only small quantities to efficiently convert large quantities of substrates into products. The reduction in enzyme quantity coupled with higher yields, lowers costs and conserves raw substrate materials while minimizing waste generation.

The "green" ethos pervades all sectors of economic development, including the pharmaceutical industry. Laviana Pharma's research and development processes are always transitioning toward cleaner and more sustainable production. Through the integration of green chemistry technologies such as enzyme catalysis, metal catalysis, and continuous production, the R&D department can significantly optimize PMI (Process Mass Intensity). Additionally, efforts to enhance energy efficiency are evident, with initiatives like solvent use reduction and solvent recovery programs. Laviana’s management of waste materials adheres to strict, compliant, and professional processes, ensuring environmentally responsible practices throughout the organization.